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237 Notably, some studies suggest that ROS-mediated inhibition of the PI3K pathway regulates cell death and enhances chemotherapy sensitivity in cancers, although the exact mechanisms are unclear 238,239 (Table 1, Fig

By neutralizing free radicals and reducing oxidative stress, glutathione can also help to prevent premature aging and improve skin texture

The degeneration of DAergic neurons contributes to the depletion of the neurotransmitter, dopamine, in the striatal neurons, resulting in motor impairment ( Recently, bioactive compounds derived from marine organisms have gained attention in the field of drug discovery for neurodegenerative diseases including PD ( Holothuria scabra ( H

This reaction, catalyzed by triose kinase (EC 2.7.1.28), also requires Mg 2+